| Antigen: |
CD54 (ICAM-1) |
| Relevance: |
ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). |
| Clone: |
BU74 |
| Subclass: |
IgM |
| Applications: |
FACS, Immunoprecipitation, Histology, Frozen |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS |
| References: |
M.P Baker et al. Blood. 1998. 92:2830-2843  |
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