| Antigen: |
CD20 |
| Relevance: |
CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues |
| Clone: |
PDR78 |
| Subclass: |
IgG |
| Applications: |
Immunohistochemistry (frozen sections), FACS |
| Immunogen: |
Pokeweed mitogen-activated Burkitt's lymphoma cell lines |
| Reactivity: |
Human |
| Species raised in: |
Mouse |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| References: |
Ono N, Sato S, Tedder TF (1997) CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI, Garland Publishing Inc., New York and London, p 135-137 |
| Notes: |
Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Click here to view Notes and Disclaimer information |
