Anti-CD21 clone BU33

Anti-CD21 Antibody Profile

Antigen:	CD21
Relevance:	CD21 (Complement receptor type 2) is a cell surface receptor for C3d (CR2) and for EB-virus that links the innate and adaptive immune response during the activation of B cells. Soluble CD21, released from the plasma membrane blocks B cell/follicular dendritic cell interaction and activates monocytes.
Clone:	BU33
Subclass:	IgG1
Applications:	FACS, Immunoprecipitation, Immunohistochemistry Frozen sections, Western blot
Immunogen:	HF B1 plaxmactyoid cell line, considered to be "late B like"
Reactivity:	Human
Species raised in:	Mouse
Fusion partner:	Non secreting plasmacytoma NSO/BALB/c mouse spleen cell; date of fusion: March 1987
Recommended growth conditions:	RPMI 1640 + 10% FCS
Epitope (if known):	FL (h)
References:	Aubry, J.P. et al. 1992 Nature 358:505-507 Bacon, K. et al. 1993 Eur.J.Immunol. 23:2721-24 Henchoz, S. et al. 1994 Immunology 81:285-90 Scholssman, S.F. et al. 1995 Leucocyte Typing V Oxford University Press Mayall, S. et al. 2001 J.Comp.Pathol. 124:83-87 Leucocyte Typing IV, 1989, Oxford University Press
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