| Antigen: |
Von Willebrand Factor |
| Relevance: |
von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis. It also helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD) |
| Clone: |
F8/44/20 |
| Subclass: |
IgG1 |
| Applications: |
Immunohistochemistry (frozen sections) |
| Immunogen: |
Von Willebrand factor isolated from human plasma |
| Reactivity: |
Human |
| Species raised in: |
Mouse |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| References: |
Naiem M, Gerdes J, Abdulaziz Z, Sunderland CA, Allington MJ, Stein H, Mason DY (l982) The value of immunohistological screening in the production of monoclonal antibodies. J Immunol Meth 50:145-160  |
| Notes: |
Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well |
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