| Antigen: |
CD4 V1 domain |
| Relevance: |
CD4 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class II molecules. CD4 cell counts are used as indicator of AIDS progression. In addition to virus binding, CD4 may have an active role in membrane fusion. |
| Clone: |
QS4120 |
| Subclass: |
IgG1 |
| Applications: |
ELISA, FACS |
| Immunogen: |
CD4+ transfectant followed by CEM cells |
| Reactivity: |
- |
| Species raised in: |
Mouse |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
Healey D et al. 1990. J. Exp. Med. 172(4):1233-1242 
Dornan S et al. 2002. J. Biol. Chem. 277(3):1912-8. |
| Notes: |
Inhibits HIV sycytium function on cocultivation assay. |
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