| Antigen: |
CD8 (Leu-2) |
| Relevance: |
CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. 14 can be used for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of T4/T8 ratios in immune deficiencies, rheumatoid arthritis, multiple sclerosis, etc. |
| Clone: |
14 |
| Subclass: |
IgG1 |
| Applications: |
Imunohistochemistry (Frozen) |
| Immunogen: |
Fibronectin purified monocytes |
| Reactivity: |
- |
| Species raised in: |
- |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM + 5% FCS. |
| References: |
Hogg N et al. 1999. J. Clin. Invest. 103(1):97-106.  |
| Notes: |
Use: T-cell enrichment by cell sorting or panning. |
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