| Antigen: |
CD8 (Leu-2) |
| Relevance: |
CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. UCH-T4 can be used for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of T4/T8 ratios in immune deficiencies, rheumatoid arthritis, multiple sclerosis, etc. |
| Clone: |
UCH-T4 |
| Subclass: |
IgG2a |
| Applications: |
Immunohistochemistry (Frozen), FACS |
| Immunogen: |
thymocytes followed by
Sezary T cells |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
- |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
Beverley P. 1982. Proc.
Royal Soc. Edin. 81B:221-232
Kee WJ et al. 2000. J. Cell Biochem. 78(1):97-111  |
| Notes: |
Antigen is a 32 kDa cell surface protein |
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