| Antigen: |
HLA-DRβ (monomorphic) |
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TDR 31.1 can be used for the identification of class II HLA molecules. Not cytotoxic with rabbit complement. |
| Clone: |
TDR 31.1 |
| Subclass: |
IgG1 |
| Applications: |
ELISA, FACS, Radioimmunoassay |
| Immunogen: |
Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line. |
| Reactivity: |
Human |
| Species raised in: |
- |
| Fusion partner: |
P3/Ns1/1-Ag4-1 |
| Recommended growth conditions: |
RPMI 1640 + 10%FCS. |
| References: |
Brodsky F et al. 1979. Immunol. Rev. 47:3-61 
De Kretser T et al. 1982. Eur. J. Immunol. 12:214-221 |
| Notes: |
Not cytotoxic with rabbit complement. Western blots to dimer and beta chain, alpha helix. 29 kDa MW |
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