| Antigen: |
HLA-DR7, DR β 1 domain. |
| Relevance: |
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 13.1 can be used for HLA typing and characterisation of B cell lines. |
| Clone: |
TAL 13.1 |
| Subclass: |
IgM |
| Applications: |
ELISA, FACS, Western blot |
| Immunogen: |
L cells transfected with the human HLA-DRB1*0701 gene |
| Reactivity: |
Human |
| Species raised in: |
Mouse |
| Fusion partner: |
P3/NS1/1-Ag4-1 |
| Recommended growth conditions: |
RPMI 1640 + 10%FCS. |
| References: |
Heyes J et al. 1991. Eur. J. Immunogenetics. 18:379-391  |
| Notes: |
Cytotoxic with rabbit complement. Western blots weakly to dimer. |
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