| Antigen: |
HPV-16 E2 (early protein E2) Epitope: aa26-45 of HPV16 (LRDHIDYWKHMRLECAFUC) |
| Relevance: |
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 271 is useful for detection of protein in cervical lesions. TVG 271 completely inhibits E2 binding to E1. |
| Clone: |
TVG 271 |
| Subclass: |
IgG1 |
| Applications: |
ELISA, Western blot |
| Immunogen: |
Maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE) |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NSO-1 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Hibma
MH et al. 1995. Eur. J. Biochem. 229:517-525 
Tchilian EZ et al. 2001. J. Immunol. 166(2):1308-13
|
| Notes: |
- |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
