| Antigen: |
HPV16 E7 (early protein E7) |
| Relevance: |
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. |
| Clone: |
TVG 701Y |
| Subclass: |
IgG2a |
| Applications: |
Western blot, ELISA, Immunohistochemistry (Frozen), FACS |
| Immunogen: |
HPV 16 E7 synthesised from s pombe |
| Reactivity: |
Human papilloma virus |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NSO-1 |
| Recommended growth conditions: |
RPMI 1640 + 15% FCS |
| References: |
Tommasino M et al. 1993. Oncogene. 8(1):195-202  |
| Notes: |
57 kDa MW. |
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