| Antigen: |
ICAM-3 (CD50) |
| Relevance: |
ICAMs are members of the
immunoglobulin superfamily that is characterised by
the presence of immunoglobulin-like domains. ICAM-3
is the major ligand for LFA-1 (CD11a/CD18) in the resting
state. ICAM-3 may play a key role in initiating
immune responses. ICAM 3.1 and ICAM 3.2 can be
used to examine LFA-1/ICAM-3 adhesion. |
| Clone: |
ICAM 3.2 |
| Subclass: |
IgG1 |
| Applications: |
Immunoprecipitation, Western blot, Radioimmunoassay, ELISA, FACS, Immunohistochemistry (Frozen) |
| Immunogen: |
ICAM-3/Fc chimric fusion
protein |
| Reactivity: |
- |
| Species raised in: |
Mouse |
| Fusion partner: |
Sp2 |
| Recommended growth conditions: |
DMEM + 5% FCS |
| References: |
Holness
CL et al. 1995. J. Biol. Chem. 270(2): 877-884 
Bossy D et al. 1995. Eur. J. Immunol. 25(2):459-465
|
| Notes: |
western gives a 130KD band |
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