| Antigen: |
p53 |
| Relevance: |
p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. PAb 1801 can be used for the specific detection of human p53 that is synthesised in the presence of p53 from other species. |
| Clone: |
PAb 1801 |
| Subclass: |
IgG1 |
| Applications: |
Immunoprecipitation, Western blot, Radioimmunoassay, ELISA, FACS, Immunohistochemistry (Frozen, Paraffin embedded) |
| Immunogen: |
Purified p53-b-galactosidase fusion proteins |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
NS-1 |
| Recommended growth conditions: |
RPMI + 10% FCS |
| References: |
Banks L et al. 1986. Eur. J. Biochem. 159:529-534. 
Cattoretti G et al. 1988. Int. J. Cancer. 41:178-183. |
| Notes: |
50 kDa MW |
For further information about antibodies from CRT or to discuss sales or licensing options, please contact us at reagents@cancertechnology.com
Please note that CRT supplies to distributors only. However, we are happy to direct researchers to the appropriate commercial party to obtain antibodies within our portfolio. Click here to view disclaimer information. |
