| Antigen: |
Phosphatidylinositol biphosphate (PIP2) |
| Relevance: |
PtdIns 4,5-P2 is a membrane phospholipid that is an important component of signal transduction pathways. |
| Clone: |
PIP2 2C11 |
| Subclass: |
IgM |
| Applications: |
ELISA, Neutralising, Immunoprecipitation, FITC |
| Immunogen: |
Liposomes (prepared in PBS with lipid A, phosphatidylcholine (PC) and cholesterol) containing synthetic di-palmitoyl PtdIns(4,5)P2. |
| Reactivity: |
Human |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Thomas CL et al. 1999. Biochem. Soc. Trans. 27:648-652. 
Osborne SL et al. 2001. J. Cell Sci. 114:2501-2511. |
| Notes: |
Reactivity: PtdIns(4,5)P2, Ptd(4)P and Ptd(3,4,5)P3.
To test antibody use a lipid blot assay as described in Thomas CL et al or a nuclear staining as in Osborne et al (full references above) |
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