| Antigen: |
XRCC2 |
| Relevance: |
XRCC2 (X-Ray Repair
Cross Complementing 2) is a RAD51 paralog. RAD51
is a eukaryotic homologue of E. coli RecA, a recombinase,
and a component of the homologous recombination DNA
repair pathway. RAD51 forms a nucleoprotein filament
(through binding RAD52 and single stranded DNA that
are exposed following double strand breaks) that initiates
recombination. XRCC2 is also components of the
homologous recombination pathway. |
| Clone: |
XRCC2 7B7/3 |
| Subclass: |
IgG1 |
| Applications: |
Western blot |
| Immunogen: |
Raised against his-tagged human XRCC2 overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page |
| Reactivity: |
- |
| Species raised in: |
Mouse: Balb/c |
| Fusion partner: |
Sp2/0 Ag.14 |
| Recommended growth conditions: |
DMEM 5% FCS |
| References: |
Masson J-Y et al. 2001. Genes Dev. 15:3296-3307. 
Cartwright R et al. 1998. Nucleic Acids Res. 26(13):3084-3089. |
| Notes: |
Positive control: HeLa nuclear extracts. Specfic- does not recognise other paralogs. 33 kDa MW |
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