Research Tools - Mouse Models

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Total results = 4


AhCre Mouse

Relevance: Cre under CYP1A1 promoter enabling inducible recombinase expression with administration of lipophilic xenobiotic (tissue-specific loxP knockout/knockin/transgene).

Bmx-Cre-ERT2 Mouse

Relevance: Cre-ERT under Bmx promoter enabling inducible conditional recombinase expression in arterial endothelial cells (tissue-specific loxP knockout/knockin/transgene). The Bmx-Cre-ERT2 mouse exhibits tissue-specific expression of an inducible Cre-ERT2 fusion protein, enabling tamoxifen-induced Cre recombinase activity in arterial endothelial cells. The Bmx-Cre-ERT2 mouse is an ideal tool in the study of gene function in angiogenesis, atherosclerosis and neovascularisation.

Cdh5(PAC)-CreERT2 Mouse

Relevance: Cdh5(PAC)-CreERT2 enable efficient inducible conditional recombinase expression in embryonic and adult endothelial cells (tissue-specific loxP knockout/knockin/transgene). The mouse is an ideal tool in the study of gene function in angiogenesis, atherosclerosis and neovascularisation.

Pdgfrb-Cre mouse

Relevance: Cre expressed under Pdgfrb promoter enabling conditional recombinase expression in pericytes and smooth vascular muscle cells (tissue-specific loxP knockout/knockin/transgene).