Anti AF10 Clone HAF10 10D3/8 Profile
| Antigen: | AF10 |
| Clone: | HAF10 10D3/8 |
| Subclass | IgG2a |
| Species Raised In: | Balb/c |
| Epitope: | Residues 1055-1069, RLSDKTGPVAQEKS. This epitope is 100% identical in human and mouse proteins |
| Cross Reactivity: | Mouse, Human |
| Applications: | ELISA, Immunoprecipitation, Western |
| Growth Conditions: | DMEM + 5% FCS |
| Fusion Partner: | Sp2/0Ag.14 |
| Relevance: | AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available. |
