Anti AF10 Clone HAF10 9A5/2 Profile

Antigen: AF10
Clone: HAF10 9A5/2
Subclass IgG2b
Species Raised In:

Balb/c

Epitope:

Residues 1055-1069, RLSDKTGPVAQEKS. This epitope is 100% identical in mouse and in human.

Cross Reactivity:

Mouse, Human

Applications: ELISA, FACS, Immunoprecipitation, Western
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: Sp2/0Ag.14
Relevance: AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available.