Anti AP-2 gamma Clone AP2g 6E4/4 Profile

Antigen: Activating Protein 2 (AP-2) gamma
Clone: AP2g 6E4/4
Subclass IgG1
Species Raised In:

Balb/c

Immunogen: Bacterially produced AP-2a/AP-2g fusion protein (c-terminal half of AP-2 gamma)
Positive Control:

MCF7 cells

Cross Reactivity:

Human, Mouse

Applications: Immunoprecipitation, Paraffin embedded, Western
Growth Conditions:

E4 + 10% FCS

Fusion Partner: Sp2/0Ag.14
Relevance: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
References:

Eloranta JJ et al. 2002. J. Biol. Chem. 277(34):30798-804. PMID: 12072434 Read more
Gee JMW et al. 2009. J. Pathol. 217(1):32-41. PMID: 18825690 Read more

Notes:

Antigen recovery will improve staining on paraffin sections.