| Antigen: | Anaphase-promoting complex (APC) 4 |
| Clone: | CIV1.1 |
| Subclass | IgG |
| Species Raised In: | Mouse |
| Immunogen: | C-terminus of APC4 |
| Epitope: | CIVIKVEKLDPELDS |
| Positive Control: | Purified APC/C by silver and mass spectrometry |
| Applications: | Immunoprecipitation, Western |
| Relevance: | APC4 is a component of the anaphase-promoting complex (APC). The APC complex functions as an ubiquitin ligase which promotes the transition from metaphase to anaphase of the cell cycle. APC4 contains WD repeats and has a molecular weight of approximately 92 kD. APC4 is located in the nucleus during interphase and at the centrosome during metaphase/anaphase. |
| Notes: | CIV1.1 may be used for the affinity purification of the Anaphase Promoticing Complex (APC/C) by peptide elution. Suggested Dilution for western blot: 1:500. |
© Cancer Research Technology 2012