Anti APC5 Clone APC5 #4 Profile
| Antigen: | Anaphase-promoting complex subunit 5 (APC5) |
| Clone: | APC5 #4 |
| Subclass | IgG1 |
| Species Raised In: | C57/bl |
| Immunogen: | GST-human APC5 |
| Epitope: | Residues 190 and 237 |
| Cross Reactivity: | Human |
| Applications: | Immunofluorescence, Immunoprecipitation, Western |
| Growth Conditions: | DME/Hepes + 8% FCS + 2mM Glutamine |
| Fusion Partner: | Sp2 |
| Relevance: | APC5 is a component of the anaphase-promoting complex/cyclosome (APC) that regulates cell cycle progression through mitosis and G1. APC5 is located in the nucleus during interphase and at the centrosome during metaphase/anaphase. The APC is inactivated by protein kinase A and is activated by CDC20 and Cdh1. |
| References: | Turnell et al. 2005. Nature. 438:690-5. PMID: 16319895 Read more |
