Anti ATG9 Clone 14F2 8B1 Profile

Antigen: Autophagy-related protein 9 (ATG9)
Clone: 14F2 8B1
Subclass Not Known
Species Raised In:

Aremenian Hamster

Immunogen: Conserved C-terminal synthetic peptide of Human ATG9 sequence
Epitope:

HPEPVPEEGSEDELPPQVHK

Positive Control:

Endogenous protein, tagged over expressed protein and sRNA-depleted HEK 293 cells,

Cross Reactivity:

Human, Rat, Mouse

Applications: Acetone, ELISA, Immunofluorescence, Immunoprecipitation, Western
Fusion Partner: P3X63Ag8.653
Relevance: Autophagy is an important process associated with infectious disease, neurodegeneration, cancer and the maintenance of cellular homeostasis. ATG9 is an essential component of the autophagy machinery and is found on autophagosomes. It is a multi-spanning membrane protein which makes it useful for sub-cellular localization studies. The detection of this protein provides important information about cell health and survival.
References:

Chan EY et al. Mol. Cell. Biol. 2009. 29(1):157-71.  PMID: 18936157 Read more

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