Anti ATMIN Clone ATMIN 11F4 Profile

Antigen: Ataxia Telangiectasia Mutated INteracting protein (ATMIN, ASCIZ)
Clone: ATMIN 11F4
Subclass IgG2a
Species Raised In:

Mouse

Immunogen: Synthetic peptide
Positive Control:

293T Cells

Cross Reactivity:

Human

Applications: Immunofluorescence, Western
Growth Conditions:

E4 + 5% FCS

Fusion Partner: Sp2/0Ag.14
Relevance: The checkpoint kinase ATM (ataxia telangiectasia mutated) transduces genomic stress signals to halt cell cycle progression and promote DNA repair in response to DNA damage. ATMIN (ATM INteracting protein) is an essential cofactor for ATM. ATMIN interacts with ATM through a C-terminal motif, which is also present in Nijmegen breakage syndrome (NBS) 1.
References:

Kanu N & Behrens A. 2007. EMBO J. 26(12):2933-41. PMID: 17525732 Read more
Maeda K et al. Dendrtic Cells. 1996. 6: 43-9