Anti BLM Clone BFL 103 Profile

Clone: BFL 103
Subclass IgG1
Species Raised In:

Balb/c

Epitope:

N-terminal domain (residues 1-447)

Positive Control:

Tonsil/thymus

Cross Reactivity:

Human

Applications: ELISA, Frozen, Western
Growth Conditions:

RPMI + 10% FCS + HAT

Fusion Partner: NS1
Relevance: BLM is the product of the Blooms syndrome gene and belongs to the RecQ family of DNA helicases. BLM is associated with an increase in the incidence of many types of cancer at an early age.
References:

Turley H et.al. 2001. Br. J. Cancer. 85(2):261-65. PMID: 11461087 Read more
Wu L et al. 2000. Biol. Chem. 275(13):9636-44. PMID: 10734115 Read more