Anti BRCA2 MTA42 Polyclonal Profile
| Antigen: | BRCA2 |
| Clone: | MTA42 |
| Species Raised In: | Rabbit |
| Immunogen: | Human BRCA2 sequence |
| Epitope: | Residues 3118-3481 at C-terminus of BRCA2 |
| Positive Control: | HeLa and U2OS human cells |
| Cross Reactivity: | Human, Mouse |
| Applications: | Immunoprecipitation, Western |
| Relevance: | Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumour suppressor gene. BRCA2 is involved in the repair of chromosomal damage, specifically in localising Rad51 to double strand breaks. BRCA2 and BRCA1 are frequently mutated in cases of hereditary breast and ovarian cancer. |
