Anti Blood group A sugar determinant Clone 9A Profile

Antigen: Blood group A sugar determinant
Clone: 9A
Subclass IgG3
Species Raised In:

Mouse

Immunogen: A431 cells (human vulval squamous carcinoma cell line)
Cross Reactivity:

Human

Applications: ELISA, Immunoprecipitation
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: P3X63Ag8
Relevance: 9A is suitable for binding to the EGF receptor in A431 cells only. These cells have a glycosylation defect which reveals otherwise cryptic sugar structures.
References:

Gullick WJ & Lemoine NR. 1990. J. Pathol. 162(3):275-6. PMID: 2266467 Read more
Parker et al. 1984. J. Biol. Chem. 259:9906-12. PMID: 6086658 Read more

Notes:

Not to be used as an EGF receptor specific reagent.