Anti BrdU Clone Bu20a Profile

Antigen: Bromodeoxyuridine (BrdU)
Clone: Bu20a
Subclass IgG1
Species Raised In:

Mouse

Immunogen: Bromodeoxyuridine conjugated to BSA
Cross Reactivity:

Human

Applications: FACS, Paraffin embedded
Growth Conditions:

RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT

Fusion Partner: NS1
Relevance: BrdU is an analogue of thymidine and is taken up into the DNA of proliferating cells. Bu20a works well in immunohistochemistry to identify cells in tissue sections or cytospin preparations that have incorporated BrdU. It is also useful to identify cells in S phase during FACS analysis.
References:

Magaud JP et al. 1989. J Histochem Cytochem 37:1517-27. PMID: 2476478 Read more

Notes:

Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well.