Anti CD1c Clone M241 Profile

Antigen: CD1c (Human Thymus Leukaemia antigen)
Clone: M241
Subclass IgG1
Species Raised In:

Balb/c

Immunogen: MOLT 4 cell line
Cross Reactivity:

Human

Applications: Immunoprecipitation
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: NS1
Relevance: Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells. M241 is useful for identification and elimination of some leukaemias.
References:

Knowles et al. 1982. Eur. J. Immunol. 12:676-81. PMID: 6754387 Read more
Small TN. 1989. Hum. Immunol. 25:181-93. PMID: 2670851 Read more
Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283 Read more
Matsumoto & Nagaki. 1986. J Immunol. 137(9):2907-12 PMID: 2428878 Read more