Anti CLEC-2 Clone 17D9 Profile
| Antigen: | C-type lectin-like receptor (CLEC-2) |
| Clone: | 17D9 |
| Subclass | IgG2b |
| Species Raised In: | Rat |
| Immunogen: | RBL-2H3 cells stably expressing HA-tagged mouse CLEC-2 |
| Epitope: | HA-tagged mouse CLEC-2 |
| Cross Reactivity: | Mouse |
| Applications: | FACS, Western |
| Growth Conditions: | RPMI + 10% FCS, 2-Mercaptoethanol and antibiotics |
| Fusion Partner: | Y3 Ag 1.2.3 |
| Relevance: | CLEC-2 belongs to a sub-family of C-type lectin receptors that signal through Syk via a single YxxL motif (hemITAM). This antibody can be used as a selective agonist of CLEC-2 and also to study its expression pattern. |
| References: | Kerrigan et al. J Immunol 2009 182:4150-7 PMID: 19299712 Read more |
| Notes: | Recommended Concentrations: 10ug/ml for FACS, 50ug/ml for agonistic activity, 2ug/ml for Western |
