Anti CR1 Clone E11 Profile

Antigen: Complement receptor 1 (CR1, CD35)
Clone: E11
Subclass IgG1
Species Raised In:

Balb/c

Immunogen: Acute monocytic leukaemia cells and normal blood monocytes.
Cross Reactivity:

Human

Applications: Acetone, Frozen, Immunoprecipitation
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: P3/ NS1/1-Ag4-1
Synonyms: C3BR
Relevance: CR1 is found on many leucocytes and binds C3b and C4b. E11 detects CR1 on most leukemic monoblasts and also normal granulocytes and may be used to define B cell lymphomas.
References:

Hogg N et al. 1984. Eur. J. Immunol. 14:236-43. PMID: 6368248 Read more
Leucocyte Typing III. Edited by AJ McMichael et al. 1987
Matthews et al. Developmental Dynamics. 2008. 237: 124-31. PMID: 18095340 Read more