| Antigen: | Cytochrome P450 1A2 |
| Clone: | D15 |
| Subclass | IgG1 |
| Species Raised In: | Mouse |
| Immunogen: | MC1a (Preparation C31B4, rat liver cytochrome P4501A2) |
| Cross Reactivity: | Human, Rat, Mouse. D15 cross reacts with CYP1A1 & CYP1A2. |
| Applications: | ELISA, Western |
| Growth Conditions: | DMEM + 5% FCS |
| Relevance: | In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans. |
© Cancer Research Technology 2012