| Antigen: | Cytochromes P450 2B1 & 2B2 |
| Clone: | b/e3 |
| Subclass | IgG1 |
| Species Raised In: | Mouse |
| Immunogen: | Rat liver cytochromes p450 2B1 and 2B2 |
| Cross Reactivity: | Rat, Mouse |
| Applications: | ELISA, Western |
| Growth Conditions: | DMEM + 5% FCS |
| Relevance: | The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. CYP2B1 and CYP2B2 are the major phenobarbital-inducible rat hepatic cytochromes P-450s. |
| References: | Leucocyte Typing V 1995. ISBN-13: 978-0192623768 |
| Notes: | Clone b/e3 inhibits PROD activity in liver microsomes of PB-treated rats and inhibits ECOD activity in liver microsomes of PB-treated but not 3MC-treated rats. The CYP2B1 antibody recognises the major barbiturate-inducible P450s in mouse and rat. |
© Cancer Research Technology 2012