| Antigen: | Cytochrome P450 (CYP3A1) |
| Clone: | p6 |
| Subclass | IgG1 |
| Species Raised In: | Mouse |
| Immunogen: | Rat liver cytochrome P450 3A1 |
| Cross Reactivity: | Human, Mouse, Rat |
| Applications: | ELISA, Western |
| Growth Conditions: | DMEM + 5% FCS |
| Relevance: | The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin. |
| Notes: | P6 is highly specific for members of the CYP 3A gene family and cross reacts with CY 3A4 in human, CYP 3A in rat and potentially CYP 3A11 (based on inducibility) in mice. |
© Cancer Research Technology 2012