| Antigen: | Cyclin Dependent Kinase 1 (Cdk1, Cdc2) |
| Clone: | Y100.4 |
| Subclass | IgG2b |
| Species Raised In: | Mouse |
| Immunogen: | Peptide spanning the C-terminal 14 residues of S. pombe Cdk1. |
| Epitope: | AKRALQQNYLRDFH |
| Cross Reactivity: | S. Pombe |
| Applications: | Western |
| Growth Conditions: | DMEM + 5% FCS |
| Fusion Partner: | Sp2 |
| Relevance: | Cdk1 (Cdc2) is a serine/threonine kinase which forms complexes with cyclins A and B which then phosphorylate a variety of target substrates to enable cell cycle progression. Therefore, Cdk1 is a marker for proliferating tumour cells. |
| References: | Radcliffe P. et al. 1998. Mol. Biol. Cell. 9(7):1757-71. PMID: 9658169Read more |
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