| Antigen: | Cyclin A |
| Clone: | AT10.2 |
| Subclass | IgG1 |
| Species Raised In: | Balb/c |
| Immunogen: | Recombinant Human Cyclin A |
| Applications: | Frozen, Paraffin embedded, Western |
| Growth Conditions: | DMEM + 10% FCS |
| Fusion Partner: | Sp2/0Ag.14 |
| Synonyms: | CCN1 antibody, CCNA antibody |
| Relevance: | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase. E23.1 is extremely sensitive for immunoblotting Cyclin A. |
| References: | Adamczewski JP et al. 1993. J. Virol. 67(11):6551-67. PMID: 8411358 Read more |
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