| Antigen: | Cytokeratin 15 |
| Clone: | LHK 15 |
| Subclass | IgG2a |
| Species Raised In: | Mouse |
| Immunogen: | Peptide sequence of cytokeratin 15 - BSA conjugate |
| Cross Reactivity: | Human, Murine, Rodent, Bovine |
| Applications: | Acetone, ELISA, Frozen, Paraffin embedded, Western |
| Growth Conditions: | DMEM + 5-10% FCS |
| Fusion Partner: | Sp2/0Ag.14 |
| Relevance: | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. |
| References: | Waseem A et al. 1999. J. Invest. Dermatol. 112:362-9. PMID: 10084315 Read more |
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