| Antigen: | Epstein Barr Virus Encoded Nuclear Antigen 2 (EBNA2) |
| Clone: | PE2 |
| Subclass | IgG1 |
| Species Raised In: | Mouse |
| Immunogen: | Recombinant fusion protein against EBNA2 |
| Epitope: | Residues 405-460 of B95.8 EBNA2 |
| Positive Control: | Immunohistochemistry (Acetone fixed): EBV positive Raji cell Line. Western blotting: B95-8 cell |
| Cross Reactivity: | Epstein Barr Virus |
| Applications: | Acetone, Frozen, Immunofluorescence, Immunoprecipitation, Western |
| Fusion Partner: | X63-Ag-8.653 |
| Relevance: | The Epstein-Barr Virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family and is one of the most common viruses in humans. EBNA2 is one of the few genes of Epstein-Barr virus which are necessary for immortalization of human primary B lymphocytes. The EBNA2 protein acts as a transcriptional activator of several viral and cellular genes. |
| References: | Young et al. 1988. J Gen Virol. 69(pt5):1051-65. PMID: 2836550Read moreYoung et al. 1989. N Engl J Med. 321(16):1080-5. PMID: 2552313Read moreRowe et al. 1991. J Exp Med. 173(1):147-58. PMID: 1845872Read moreNiedobitek et al. 1995. Blood. 86(2):659-65. PMID: 7605996Read more |
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