Anti EBV-LMP-1 Clone CS 1-4 Profile

Antigen: Epstein-Barr Virus, Latent Membrane Protein 1 (EBV-LMP-1)
Clone: CS 1-4
Subclass IgG1
Species Raised In:

Mouse

Epitope:

CS-1: residues 372-382 of wt-EBV LMP1. CS-2: residues 197-386 of wt EBV LMP1. CS-3&4: residues 252-298 of wt EBV LMP1.

Positive Control:

EBV transformed lymphoblastoid cell lines

Cross Reactivity:

Human

Applications: Acetone, Frozen, Immunoprecipitation, Paraffin embedded, Western
Fusion Partner: X63-Ag-8.653
Relevance: CS 1-4 is specific for Epstein-Barr virus infected cells expressing the latent membrane protein (LMP). This is in fact four pooled antibodies which collectively detect LMP's encoded by each of 20 geographically distinct EBV isolates.
References:

Rowe M et al. 1987. J Gen Virol 68(Pt6):1575-86. PMID: 2438376 Read more
Rowe M et al. 1987. EMBO J 6(9):2743-51. PMID: 2824192 Read more
Ascani S et al. 1997. Annals of Oncology 8(11): 1133-8. PMID: 9426333 Read more
Nakatsuka S et al. 2002. Journal of Clinical Oncology, Vol 20(20):4255-60. PMID: 12377970 Read more
Rowe M et al. 1987. J Gen Virol 68(Pt6):1575-86. PMID: 2438376 Read more
Flanagan J et al. 2003. J Gen Virol 84(Pt7):1871-9. PMID: 12810882 Read more
Xu J et al. 2002. J Virol 76(8):4080-6. PMID: 11907247 Read more