| Antigen: | ErbB4 (Her4, p180erbB4) |
| Clone: | HFR1 |
| Subclass | IgG2b |
| Species Raised In: | Balb/c |
| Immunogen: | Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein (residues 1249-1264.) |
| Applications: | Immunoprecipitation, Paraffin embedded, Western |
| Growth Conditions: | DMEM + 10% FCS |
| Fusion Partner: | Sp2 |
| Synonyms: | Proto-oncogene-like protein c-ErbB-4 antibody, Receptor protein tyrosine kinase erbB 4 precursor antibody, Avian erythroblastic leukemia viral (verbb2) oncogene homolog 4 antibody, Tyrosine kinase type cell surface receptor HER4 antibody |
| Relevance: | The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB4 is involved in cell growth regulation and its expression or function may be altered in human cancers. |
| References: | Srinivasan R et al. 1998. J. Pathol 185:236-45. PMID: 9771476 Read more |
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