Anti HLA-DRa Clone TAL 1B5 Profile

Antigen: Human Leukocyte Antigen DR, alpha subunit
Clone: TAL 1B5
Subclass IgG1
Species Raised In:

Mouse

Immunogen: Bristol 8 separated alpha chain preparation
Cross Reactivity:

Human

Applications: Acetone, ELISA, Frozen, Paraffin embedded, Western
Growth Conditions:

RPMI 1640 + 10% FCS

Fusion Partner: P3/ NS1/1-Ag4-1
Relevance: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 1B5 may be used for HLA typing.
References:

Adams TE et al. 1983. Immunology. 50(4):613-24. PMID: 6197354Read more

Notes:

TAL 1B5 can detect both dimers and the DR alpha chain by western blot.