| Antigen: | Human Papilloma Virus-16 early protein 2 (HPV16-E2) |
| Clone: | TVG 261 |
| Subclass | IgG1 |
| Species Raised In: | Balb/c |
| Immunogen: | Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE). |
| Epitope: | Residues 2-17. ETLCQRLNVCQDKILT |
| Applications: | ELISA, Western |
| Growth Conditions: | DMEM + 5% FCS |
| Fusion Partner: | NSO1 |
| Relevance: | The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions. |
| References: | Hibma MH et al. 1995. Eur. J. Biochem. 229:517-25. PMID: 7744075Read more |
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