Anti INFa Clone ST29 Profile

Antigen: Interferon alpha (INFa)
Clone: ST29
Subclass IgG1
Species Raised In:

Balb/c

Immunogen: Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN)
Positive Control:

PMA stimulated human peripheral blood mononuclear cells

Cross Reactivity:

Human

Applications: Neutralising
Growth Conditions:

RPMI 1640 + 10% FCS

Fusion Partner: NS2
Relevance: INFa is a type I interferon that is involved in the innate immune response against viral infections. ST29 distinguishes between sub-species of human INFa and can be used to detect INF oligomers. Neutralises anti-viral activity of INF.
References:

Shearer M et al. 1984. J. Immunol. 133: 3096-101. PMID: 6491281Read more