Anti Kidins220/ARMS Clone p220 1F8/3 Profile

Antigen: Kidins220/ARMS
Clone: p220 1F8/3
Subclass IgG1
Species Raised In:

Balb/c

Immunogen: Recombinant GST-Kidins220/ARMS (last 347 amino acids at the carboxy terminus) fusion protein.
Applications: ELISA, Immunoprecipitation, Paraffin embedded, Western
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: Sp2/0Ag.14
Relevance: Kidins220/ARMS (Kinase D-Interacting Substrate of 220 kDa, ARMS; Ankyrin Repeat-rich Membrane Spanning) is an integral membrane protein that is selectively expressed in brain and neuroendocrine cells and phosphorylated by PKD (protein Kinase D). Kidins220 has also been shown to function downstream of the Trk and Eph receptor tyrosine kinases.
References:

Iglesias T et al. 2000. J. Biol. Chem. 275:40048-56. PMID: 10998417Read more
Niedobitek et al. 1995. Blood. 86(2):659-65. PMID: 7605996 Read more