Anti Keratin 19 Clone LAS86 Profile

Antigen: Cytokeratin 19
Clone: LAS86
Subclass IgM
Species Raised In:

Mouse

Cross Reactivity:

Human

Applications: Immunohistochemistry
Relevance: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 restricted 'in situ' to differentiated urothelium. Useful in the studies of epithelial cells and tumor origin.
References:

von Koskull et al. 1984. Hum Genet. 65:262-7. PMID:6199284 Read more