Anti PD-ECGF Clone PGF 44C Profile

Antigen: Platelet-derived endothelial cell growth factor (thymidine phosphorylase); PD-ECGF.
Clone: PGF 44C
Subclass IgG1
Species Raised In:

Mouse

Immunogen: Full length human protein in E. coli
Positive Control:

HUVEC cell or breast carcinoma

Cross Reactivity:

Human

Applications: Acetone, Frozen, Immunoprecipitation, Paraffin embedded, Western
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: NS1
Relevance: PD-ECGF expression is elevated in breast tumours and is a prognostic factor in colon tumours.
References:

Moghaddam A et al. 1995. Proc. Natl. Acad. Sci. USA. 92(4):998-1002. PMID: 7532308Read more
Fox SB et al. 1995. J. Pathol. 176(2):183-190. PMID: 7636628Read more
Fox SB et al.  1997. Ann. Oncol. 8(3):271-275. PMID: 9137797Read more
Giatromanolaki A et al. 2003. J. Pathol. 200(2):222-8. PMID: 12754744Read more

Notes:

PGF 44C blocks enzyme activity.