Anti RAET1E Clone 119/6/17/2 Profile
| Antigen: | RAET1E |
| Clone: | 119/6/17/2 |
| Subclass | IgG2b |
| Species Raised In: | Mouse |
| Immunogen: | Recombinant His-tagged protein to human extra-cellular domain of RAET1E produced in E.coli (33-227) with a N terminal 6x His tag |
| Epitope: | Residues 33-227 |
| Positive Control: | Stable RAET1E cell line |
| Cross Reactivity: | Human |
| Applications: | ELISA, FACS, Immunofluorescence, Immunoprecipitation, Neutralising, Western |
| Relevance: | RAET1E (retinoic acid early transcript 1E), or ULBP4, is a member of the RAET1 family of major histocompatibility complex (MHC) class I-related genes. RAET1E and RAET1G differ from the other RAET1 proteins by having a type I membrane-spanning sequence at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a functional ligand for NKG2D, which causes lymphocyte activation resulting in the secretion of cytokines. |
| References: | Bacon et al. 2004. J Immunol. 173:1078-84. PMID: 15240696 Read more |
