Anti SV40 LT Clone LP7N Profile

Antigen: SV40 large T anitgen
Clone: LP7N
Subclass IgG1
Species Raised In:

Mouse

Immunogen: Detergent insoluble fraction of SVK14 cell line (SV40 transformed neonatal keratinocytes)
Epitope:

A region of the SV40 T antigen which is not covered by small t-shared domain or ND2 protein, since both are negative. This

Applications: Frozen
Growth Conditions:

DMEM + 5% FCS

Relevance: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.