Anti TCP-1a Clone 91a Profile

Antigen: T-complex polypeptide 1 alpha (TCP-1a)
Clone: 91a
Subclass IgG2a rat
Species Raised In:

Rat

Immunogen: C-terminal half of the full length murine TCP protein
Epitope:

465 AKLRA

Positive Control:

Mouse spleen and LHK35.2 cells

Cross Reactivity:

Human, Murine, Rat, Canine, Rabbit, Bovine, Porcine, Yeast

Applications: Immunoprecipitation, Western
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: Y3 Ag 1.2.3
Synonyms: AI528772, CCT, Cct1, Ccta, TRic, Tcp-1, Tp63, c-cpn, p63
Relevance: TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.
References:

Harrison-Lavoie et al. 1993. EMBO J . 12:2847-53. PMID: 8335000 Read more
Sternlicht H et al. 1993. PNAS USA 90:9422-6. PMID: 8105476 Read more
Willison K et al. 1989. Cell. 57:621-32. PMID: 2655925 Read more