Anti XRCC2 Clone XRCC2 1G4/1 Profile

Antigen: X-Ray Repair Cross Complementing 2 (XRCC2)
Clone: XRCC2 1G4/1
Subclass IgG1
Species Raised In:

Balb/c

Positive Control:

HeLa nuclear extracts

Cross Reactivity:

Human, Hamster

Applications: Western
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: Sp2/0Ag.14
Relevance: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
References:

French CA et al. 2002. J. Biol. Chem. 277(22):19322-30. PMID: 11912211Read more

Notes:

XRCC2 1G4/1 does not recognise other paralogs.