| Antigen: | Zebrafish DeltaC |
| Clone: | zdc2 (DLC 7D3/1) |
| Subclass | IgG2a |
| Species Raised In: | Balb/c |
| Immunogen: | Extracellular region of zebrafish DeltaC protein |
| Epitope: | DeltaC extracellular domain |
| Positive Control: | HEK293 cells transfected with DeltaD and Zebrafish embryo cryosections (formulin fixed) |
| Cross Reactivity: | Zebrafish |
| Applications: | ELISA, FACS, Frozen, Western |
| Fusion Partner: | Sp2/0Ag.14 |
| Relevance: | Delta proteins activate Notch through a binding reaction that depends on their extracellular domains. During somitogenesis, Notch signalling via DeltaC keeps the oscillations of neighbouring cells in synchrony. DeltaC is also expressed in subsets of cells in the nervous system and elsewhere. |
| References: | Guidicelli et al. PLoS Biol. 2007. 5:1309-1323. PMID: 17535112Read more |
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